This product consists of the immunoglobulin fraction of rabbit anti-S-100 serum.The antibody was generated in rabbits against S-100 protein isolated from bovine brain.
Common determinants on this protein occur amongst widely disparate species, e.g. fruit fly and man. Anti-S-100 reacts with the alpha and beta subunits of S-100A. In the central nervous system, glial and ependymal cells stain positively. In the peripheral nervous system, Schwann cells are positively labeled. Melanocytes and Langerhans cells stain in skin.
Photo Description: IHC image of a human astrocytoma staining for s-100 beta. The tissue was formalin fixed and embedded in paraffin, before microtome sectioning and antigen retrieval. Sections were incubated at RT in 10% goat serum in PBS, before standard IHC procedure. Primary antibody was incubated at 1:5000 for 48 hours, goat anti-rabbit secondary was subsequently added for 1 hour after washing with PBS. Light microscopy staining was achieved with standard biotin-streptavidin/HRP procedure and DAB chromogen.
Quantity / Volume: 6 mL
Reacts With: Bullfrog, Ferret, Fish, Gerbil, Human, Monkey, Mouse, Rat
Availability: In Stock
Alternate Names: S-100 protein alpha chain; S-100 protein subunit alpha; S100 alpha; S100 calcium-binding protein A1; S100A; S100 calcium binding protein A1, anti-S100
Gene Symbol: S100A1