nNOS:C-Terminal (Neuronal Nitric Oxide Synthase)

nNOS:C-Terminal (Neuronal Nitric Oxide Synthase)
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Price: $350.00
Product ID : 24287

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Description

The ImmunoStar neuronal nitric oxide synthase C-terminal antiserum was quality control tested using standard immunohistochemical methods. The antiserum demonstrates strongly positive labeling of rat hypothalamus, striatum, cortex and spinal cord using indirect immunofluorescent and biotin/avidin-HRP techniques. Recommended primary dilution is 1/8,000 - 1/12,000 in PBS/0.3% Triton X-100 - Bn/Av-HRP Technique.

By Western blot analysis of brain homogenates the antibody specifically labels a band of approximately 155 kD. Immuno-labeling is completely abolished by pre-adsorption with synthetic human nNOS (1419-1433) at 5 µg per mL of diluted antibody. No cross reactivity with other forms of NOS were observed. 

Photo Description: IHC image of a single neuron staining for the C-terminal of nNOS in the rat cortex (above), along with low magnification of cortex (below left), neurons in the rat dentate gyrus (below middle) and in the striatum (below right). The tissue was fixed with 4% formaldehyde in phosphate buffer, before being removed and prepared for vibratome sectioning. Floating sections were incubated at RT in 10% goat serum in PBS, before standard IHC procedure. Primary antibody was incubated at 1:10000 for 48 hours, goat anti-rabbit secondary was subsequently added for 1 hour after washing with PBS. Light microscopy staining was achieved with standard biotin-streptavidin/HRP procedure and DAB chromogen, below middle image with nickel stain.

 nNos C-Terminal cortex #24287    nNOS-C-terminal striatum #24287


Host: Rabbit

Quantity / Volume:  100 µL

State: Lyophilized Whole Serum

Reacts With: Cat, Chick, Ferret, Guinea Pig, Hamster, Human, Monkey, Mouse, Opossum, Rat, Shrew, Squirrel Monkey, Vole, Zebrafish

Availability: In Stock

Alternate Names:  Constitutive NOS; NC-NOS; NOS type I; Neuronal NOS; Nitric Oxide Synthase; bNOS; Nitric oxide synthase-brain; N-NOS; Peptidyl-cysteine S-nitrosylase; IHPS1; NC-NOS; nitric oxide synthase 1 (neuronal), anti-nNos:C-Terminal

Gene Symbol / ID, Accession #:  NOS1, 4842

RRID:  AB_572256

Reviews

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Reviewed by ld2596
03/19/2015 - 02:10:46 PM
Fantastic antibody!

We have used this antibody to stain for nNOS positive neurons (also stains some processes) in frozen tissue sections and whole mount preparations of mouse intestine. We get consistent staining at 1:1500 although the staining of the neurons is so strong this can probably be dropped, even for quantification purposes!

Tissue prep:
4% PFA/PBS for 1.5 hrs, cryoprotected in 30% sucrose until they sink, OCT embedded, and sectioned.
For whole mounts, we open up intestine and fix in 4% PFA/PBS for 1.5 hrs.

IF protocol:
Sections:
Rehydrate in PBS, block with HINGS, stain in primary @4C O/N.
Wmts:
Wash in PBST, stain in primary with HINGS and DMSO @4C 48 hrs.

Sections:
Wash with PBS, stain with Alexafluor secondaries (Invitrogen), wash with PBS, and DAPI mount.
Wmts:
Wash in PBST, stain in secondary with HINGS and DMSO @RT 48 hrs.
Optional: proceed with MeOH dehydration and optical clearing.

Meenakshi Rao, MD PhD
Assistant Professor of Pediatrics
Columbia University Medical Center
New York, NY 10032

Publications

PROD # ANTIBODY CITATION SPECIES REACTIVITY APPL METHOD RESEARCH AREA # CITED BY PUBMED ID
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Gammie, Stephen C., Uade B. Olaghere-da Silva, and Randy J. Nelson. "3-Bromo-7-nitroindazole, a neuronal nitric oxide synthase inhibitor, impairs maternal aggression and citrulline immunoreactivity in prairie voles." Brain research 870.1 (2000): 80-86. Vole 18 10869504
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Wang, B., et al. "A canine minidystrophin is functional and therapeutic in mdx mice." Gene therapy 15.15 (2008): 1099-1106. Mouse IHC 33 18432277
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody J Physiol. 2003 May 1;548(Pt 3):731-43. Epub 2003 Mar 14. A novel O2-sensing mechanism in rat glossopharyngeal neurones mediated by a halothane-inhibitable background K+ conductance. Campanucci VA1, Fearon IM, Nurse CA. Rat IF 12640017
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Erichsen, Jonathan T., and Paul J. May. "A perioculomotor nitridergic population in the macaque and cat." Investigative ophthalmology & visual science 53.9 (2012): 5751-5761. Cat, Monkey 1 22836763
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Gordon, MD, FACE, Donald L., et al. "A SPURIOUS MARKEDLY INCREASED SERUM ESTRADIOL LEVEL DUE TO AN IgA LAMBDA." Endocrine Practice 5.2 (1999): 80-83. 0 15251694
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Gelman, Diego, et al. "A wide diversity of cortical GABAergic interneurons derives from the embryonic preoptic area." The Journal of Neuroscience 31.46 (2011): 16570-16580. Mouse IHC 25 22090484
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Adams, Marvin E., The Journal of cell biology 150.6 (2000): 1385-1398.et al. "Absence of syntrophin leads to structurally aberrant neuromuscular synapses deficient in utrophin." Mouse IF 174 10995443
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Rijkers, Kim, et al. "Acute seizure-suppressing effect of vagus nerve stimulation in the amygdala kindled rat." Brain research 1319 (2010): 155-163. Rat IHC 11 20079342
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Gotti, Stefano, et al. "Alteration of NO-producing system in the basal forebrain and hypothalamus of Ts65Dn mice: an immunohistochemical and histochemical study of a murine model for Down syndrome." Neurobiology of disease 16.3 (2004): 563-571. Mouse 16 15262268
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Martini, M., et al. "Androgen receptors are required for full masculinization of nitric oxide synthase system in rat limbic Rat 16 18582470
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Wang, Gang, et al. "Angiotensin II type 2 receptor-coupled nitric oxide production modulates free radical availability and voltage-gated Ca2+ currents in NTS neurons." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 302.9 (2012): R1076-R1083. Mouse, Rat 12 22378773
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Susaki, Etsuko, et al. "Apelin cells in the rat stomach." Regulatory peptides 129.1 (2005): 37-41. Rat 43 not found
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Westendorp, Rudi GJ, et al. "Atrial natriuretic peptide improves pulmonary gas exchange in subjects exposed to hypoxia." American Review of Respiratory Disease 148 (1993): 304-304. Hypoxia 24 8393637
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Mercado, Mary Lynn, et al. "Biglycan targets dystrobrevin, syntrophin and nNOS to the muscle cell membrane." The FASEB journal: official publication of the Federation of American Societies for Experimental Biology 20.10 (2006): 1724. Mouse 1 not found
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Jaffrey, Samie R., et al. "CAPON: a protein associated with neuronal nitric oxide synthase that regulates its interactions with PSD95." Neuron 20.1 (1998): 115-124. Rat IHC 296 9459447
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Yip, Yee Ping, et al. "Cdk5 selectively affects the migration of different populations of neurons in the developing spinal cord." Journal of Comparative Neurology 503.2 (2007): 297-307. Mouse 15 17492640
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Wang, C., et al. "Changes in the innervation of the mouse internal anal sphincter during aging." Neurogastroenterology & Motility 25.7 (2013): e469-e477. Mouse IF aging 2 23634828
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Behan, Mary, et al. "Chemoarchitecture of GABAergic neurons in the ferret superior colliculus." Journal of Comparative Neurology 452.4 (2002): 334-359. Ferret 32 12355417
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Coleman, Christal G., et al. "Chronic intermittent hypoxia induces NMDA receptor-dependent plasticity and suppresses nitric oxide signaling in the mouse hypothalamic paraventricular nucleus." The Journal of Neuroscience 30.36 (2010): 12103-12112. Mouse Hypoxia 25 20826673
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Lu, Yuefeng, et al. "Coexpression of serotonin and nitric oxide in the raphe complex: cortical versus subcortical circuit." The Anatomical Record 293.11 (2010): 1954-1965. Rat IF 9 20734426
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Domoto, Tokio, and Toshiko Tsumori. "Co-localization of nitric oxide synthase and vasoactive intestinal peptide immunoreactivity in neurons of the major pelvic ganglion projecting to the rat rectum and penis." Cell and tissue research 278.2 (1994): 273-278. Rat 31 7528096
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Fuentes-Santamaria, Veronica, et al. "Cortex contacts both output neurons and nitrergic interneurons in the superior colliculus: direct and indirect routes for multisensory integration." Cerebral Cortex 18.7 (2008): 1640-1652. Cat 15 18003596
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Thclma Suely, O. K. A. Y., et al. "DETECTION OF EBV-DNA IN SERUM SAMPLES OF AN IMMUNOSUPPRESSED CHILD DURING A THREE YEARS FOLLOW-UP: ASSOCIATION OF CLINICAL AND PCR DATA WITH ACTIVE INFECTION." Revista Do Instituto de Medicina Tropical de S Human DNA 0 15880222
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Leshan, Rebecca L., et al. "Direct innervation of GnRH neurons by metabolic-and sexual odorant-sensing leptin receptor neurons in the hypothalamic ventral premammillary nucleus." The Journal of Neuroscience 29.10 (2009): 3138-3147. Mouse IHC metabolic 82 19279251
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Microsc Res Tech. 2005 Sep;68(1):13-35. Distribution of nitric oxide synthase immunoreactivity in the mouse brain.Gotti S1, Sica M, Viglietti-Panzica C, Panzica G. Mouse IHC 16208717
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Horne, Eric A., et al. "Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington's disease and mouse models." European Journal of Neuroscience 37.3 (2013): 429-440. Mouse, Human huntington 4 23167744
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Neuroscience. 2010 Jan 13;165(1):116-29. doi: 10.1016/j.neuroscience.2009.09.076. Epub 2009 Oct 2. Dynamic expression of the Onecut transcription factors HNF-6, OC-2 and OC-3 during spinal motor neuron development. Francius C1, Clotman F. Transcription Factor 17 19800948
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Dystroglycan is not required for localization of dystrophin, syntrophin, and neuronal nitric-oxide synthase at the sarcolemma but regulates integrin - 7B expression and 54 not found
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Yang, Ying-Ying, et al. "Effect of 1-week losartan administration on bile duct-ligated cirrhotic rats with portal hypertension." Journal of hepatology 36.5 (2002): 600-606. Rat 24 11983442
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Martini, M., et al. "Effects of perinatal administration of bisphenol A on the neuronal nitric oxide synthase expressing system in the hypothalamus and limbic system of CD1 mice." Journal of neuroendocrinology 22.9 (2010): 1004-1012. Mouse IHC 14 20561153
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Putnam, Susan K., et al. "Effects of testosterone metabolites on copulation, medial preoptic dopamine, and NOS-immunoreactivity in castrated male rats." Hormones and behavior 47.5 (2005): 513-522. Rat 40 15811352
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Akingba, A. George, and Arthur L. Burnett. "Endothelial nitric oxide synthase protein expression, localization, and activity in the penis of the alloxan-induced diabetic rat." Molecular urology 5.4 (2001): 189-197. Rat 85 11790282
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Knoll, John Gabriel, Cory A. Wolfe, and Stuart A. Tobet. "Estrogen modulates neuronal movements within the developing preoptic area Mouse IHC 28 17767488
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Sica, Monica, et al. "Estrous cycle influences the expression of neuronal nitric oxide synthase in the hypothalamus and limbic system of female mice." BMC neuroscience 10.1 (2009): 78. Mouse IHC 25 19604366
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Campanucci VA1, Zhang M, Vollmer C, Nurse CA, J Neurosci. 2006 Sep 13;26(37):9482-93. "Expression of multiple P2X receptors by glossopharyngeal neurons projecting to rat carotid body O2-chemoreceptors: role in nitric oxide-mediated efferent inhibition" Rat 37 16971532
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Buffo, Annalisa, et al. "Extrinsic regulation of injury/growth?related gene expression in the inferior olive of the adult rat." European Journal of Neuroscience 18.8 (2003): 2146-2158. Rat 27 14622175
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Sezen, S. F., et al. "FK506 binding protein 12 is expressed in rat penile innervation and upregulated after cavernous nerve injury." International journal of impotence research 14.6 (2002). Rat IHC 32 12494287
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Percival, Justin M., et al. "Golgi and sarcolemmal neuronal NOS differentially regulate contraction-induced fatigue and vasoconstriction in exercising mouse skeletal muscle." The Journal of clinical investigation 120.3 (2010): 816. Mouse IHC 55 20124730
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Wu, Yuanyuan, et al. "Hoxc10 and Hoxd10 regulate mouse columnar, divisional and motor pool identity of lumbar motoneurons." Development 135.1 (2008): 171-182. Mouse IHC 48 18065432
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Montoli, A., G. Colussi, and L. Minetti. "Hypercalcemia in Addison's disease: calciotropic hormone profile and bone histology." Journal of internal medicine 232.6 (1992): 535-540. 28 1474363
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Shin, Dong Hoon, et al. "Immunocytochemical localization of neuronal and inducible nitric oxide synthase in the retina of zebrafish,Brachydanio rerio." Neuroscience letters 292.3 (2000): 220-222. Zebrafish IHC 22 11018316
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Kumano, A., et al. "Immunohistochemical Localization of Gastrin?releasing Peptide, Neuronal Nitric Oxide Synthase and Neurone?specific Enolase in the Uterus of the North American Opossum, Didelphis virginiana." Anatomia, histologia, embryologia 34.4 (2005): 225-231. Opossum IHC 0 15996123
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Llewellyn-Smith, Ida J., and Greta JE Gnanamanickam. "Immunoperoxidase detection of neuronal antigens in full-thickness whole mount preparations of hollow organs and thick sections of central nervous tissue." Journal of neuroscience methods 196.1 (2011): 1-11. 4 21167203
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Pajolla, Gisela P., et al. "Immunoreactivity for neuronal NOS and fluorescent indication of NO formation in the NTS of juvenile rats submitted to chronic intermittent hypoxia." Autonomic Neuroscience 148.1 (2009): 55-62. Rat Hypoxia 9 19345616
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Trainor, Brian C., et al. "Impaired nitric oxide synthase signaling dissociates social investigation and aggression." Behavioral neuroscience 121.2 (2007): 362. Mouse IHC 24 17469926
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Adams, Marvin E., Heather A. Mueller, and Stanley C. Froehner. "In vivo requirement of the -syntrophin PDZ domain for the sarcolemmal localization of nNOS and aquaporin-4." The Journal of cell biology 155.1 (2001): 113-122. Mouse IF 153 11571312
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Lee, Sunhee C., et al. "Inducible nitric oxide synthase immunoreactivity in the Alzheimer disease hippocampus: association with Hirano bodies, neurofibrillary tangles, and senile plaques." Journal of Neuropathology & Experimental Neurology 58.11 (1999): 1163-1169. alzheimer 99 10560659
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Gnanamanickam, Greta JE, and Ida J. Llewellyn-Smith. "Innervation of the rat uterus at estrus: A study in full-thickness, immunoperoxidase?stained whole-mount preparations." Journal of Comparative Neurology 519.4 (2011): 621-643. Rat IHC 11 21246547
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Oboti, L., et al. "Integration and sensory experience?dependent survival of newly?generated neurons in the accessory olfactory bulb of female mice." European Journal of Neuroscience 29.4 (2009): 679-692. Mouse IHC 33 19200078
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Lagou, Magdalini, et al. "Interstitial cells and phasic activity in the isolated mouse bladder." BJU international 98.3 (2006): 643-650. Mouse IHC 45 16925766
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Kohlmeier, Kristi A., et al. "Knockouts reveal overlapping functions of M2 and M4 muscarinic receptors and evidence for a local glutamatergic circuit within the laterodorsal tegmental nucleus." Journal of neurophysiology 108.10 (2012): 2751. Mouse ICC 2 22956788
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody J Neurosci. 2006 Jun 28;26(26):6924-34. Layer acquisition by cortical GABAergic interneurons is independent of Reelin signaling. Pla R1, Borrell V, Flames N, Marín O. Mouse IF 16807322
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Leshan, Rebecca L., et al. "Leptin action through hypothalamic nitric oxide synthase-1-expressing neurons controls energy balance." Nature medicine 18.5 (2012): 820-823. Mouse 21 22522563
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody J Comp Neurol. 2012 Apr 15;520(6):1198-211. doi: 10.1002/cne.22768. Lis1 reduction causes tangential migratory errors in mouse spinal cord. Moore KD1, Chen R, Cilluffo M, Golden JA, Phelps PE. Mouse IHC 21935943
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody CAO, QI-LIN, HEATHER A. MURPHY, and HEYWOOD M. PETRY. "Localization of nitric oxide synthase in the tree shrew retina." Visual neuroscience 16.03 (1999): 399-409. Shrew 12 10349961
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Lagou, Magdalini, et al. "Location of interstitial cells and neurotransmitters in the mouse bladder." BJU international 97.6 (2006): 1332-1337. Mouse IF 31 16686734
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Yip, Yee Ping, et al. "Location of preganglionic neurons is independent of birthdate but is correlated to reelin?producing cells in the spinal cord." Journal of Comparative Neurology 475.4 (2004): 564-574. Mouse 12 15236237
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Katz, Jonathan P., et al. "Loss ofKlf4 in mice causes altered proliferation and differentiation and precancerous changes in the adult stomach." Gastroenterology 128.4 (2005): 935-945. Mouse cancer 154 15825076
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Watkins, Crystal C., Solomon H. Snyder, and Christopher D. Ferris. "Methods for prevention and treatment of gastrointestinal disorders." U.S. Patent No. 6,774,128. 10 Aug. 2004. 3 not found
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Yip, Yee Ping, Christine Capriotti, and Joseph W. Yip. "Migratory pathway of sympathetic preganglionic neurons in normal and reeler mutant mice." Journal of Comparative Neurology 460.1 (2003): 94-105. Mouse 19 12687699
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Khanna, Sangeeta, et al. "Molecular organization of the extraocular muscle neuromuscular junction: partial conservation of and divergence from the skeletal muscle prototype." Investigative ophthalmology & visual science 44.5 (2003): 1918-1926. Mouse IHC 28 12714624
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Carrillo, Beatriz, et al. "Morphometrical and neurochemical changes in the anteroventral subdivision of the rat medial amygdala during estrous cycle." Brain research 1150 (2007): 83-93. Rat 30 17425950
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Martin, Lee J., et al. "Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase?1 transgenic mice: Mechanisms of mitochondriopathy and cell death." Journal of Comparative Neurology 500.1 (2007): 20-46. Mouse IHC 159 17099894
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Magno, Lorenza, et al. "Multiple embryonic origins of nitric oxide synthase-expressing GABAergic neurons of the neocortex." Frontiers in neural circuits 6 (2012). Mouse IHC 6 23015780
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Krolick, Keith A. "Muscle-derived nitric oxide synthase expression, differences associated with muscle fiber-type, and disease susceptibility in a rat model of myasthenia gravis." Clinical Immunology 121.3 (2006): 286-293. Rat IF 7 16938490
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Gamage, P. P. K. M., et al. "Myenteric neuron numbers are maintained in aging mouse distal colon." Neurogastroenterology & Motility 25.7 (2013): e495-e505. Mouse IHC aging 8 23517051
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Collado, Paloma, et al. "NADPH-diaphorase activity increases during estrous phase in the bed nucleus of the accessory olfactory tract in the female rat." Brain research 983.1 (2003): 223-229. 12 12914984
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Garfield, Alastair S., et al. "Neurochemical characterization of body weight-regulating leptin receptor neurons in the nucleus of the solitary tract." Endocrinology 153.10 (2012): 4600-4607. Mouse IF,IHC 15 22869346
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Eliasson, Mikael JL, et al. "Neuronal nitric oxide synthase activation and peroxynitrite formation in ischemic stroke linked to neural damage." The Journal of neuroscience 19.14 (1999): 5910-5918. Mouse IHC 312 10407030
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Eliasson, Mikael JL, et al. "Neuronal nitric oxide synthase alternatively spliced forms: prominent functional localizations in the brain." Proceedings of the National Academy of Sciences 94.7 (1997): 3396-3401. Mouse IF 240 9096405
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Edelmann, Michelle, et al. "Neuronal nitric oxide synthase and calbindin delineate sex differences in the developing hypothalamus and preoptic area." Developmental neurobiology 67.10 (2007): 1371-1381. Mouse 37 17638388
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Sato, Satoru, et al. "Neuronal nitric oxide synthase and gonadal steroid interaction in the MPOA of male rats: co-localization and testosterone-induced restoration of copulation and nNOS-immunoreactivity." Brain research 1043.1 (2005): 205-213. Rat 43 15862534
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Downen, Martha, et al. "Neuronal nitric oxide synthase expression in developing and adult human CNS." Journal of Neuropathology & Experimental Neurology 58.1 (1999): 12-21. Human ICC 55 10068309
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Travers, Joseph B., et al. "Neurotransmitter phenotypes of intermediate zone reticular formation projections to the motor trigeminal and hypoglossal nuclei in the rat." Journal of Comparative Neurology 488.1 (2005): 28-47. Rat IHC 54 15912497
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Singh, Sanjay, Thackery Gray, and Robert D. Wurster. "Nitric oxide and carbon monoxide synthesizing enzymes and soluble guanylyl cyclase within neurons of adult human cardiac ganglia." Autonomic Neuroscience 145.1 (2009): 93-98. Human 4 19106038
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Papka, Raymond E., et al. "Nitric oxide nerves in the uterus are parasympathetic, sensory, and contain neuropeptides." Cell and tissue research 279.2 (1995): 339-349. 58 7534654
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Abe, Sumiko, et al. "Nitric oxide synthase expressions in rat dorsal root ganglion after a hind limb tourniquet." Neuroreport 14.17 (2003): 2267-2270. Rat 10 14625460
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Neuroscience. 1994 Mar;59(2):429-45. Nitric oxide synthase immunoreactivity in rat pontine medullary neurons. Dun NJ1, Dun SL, Förstermann U. Rat 173 7516501
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Development. 2012 Sep;139(17):3109-19. doi: 10.1242/dev.078501. Epub 2012 Jul 25.Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification. Roy A1, Francius C, Rousso DL, Seuntjens E, Debruyn J, Luxenhofer G, Huber AB, Huylebroeck D, Novitch BG, Clotman F. Mouse IF Transcription Factor 8 22833130
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Calupca, Michelle A., Margaret A. Vizzard, and Rodney L. Parsons. "Origin of neuronal nitric oxide synthase (NOS)?immunoreactive fibers in guinea pig parasympathetic cardiac ganglia." Journal of Comparative Neurology 426.3 (2000): 493-504. Guinea Pig 28 10992251
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Exp Brain Res. 2005 Jul;164(3):286-300. Epub 2005 Jun 7. Otolith organ or semicircular canal stimulation induces c-fos expression in unipolar brush cells and granule cells of cat and squirrel monkey. Sekerková G1, Ilijic E, Mugnaini E, Baker JF. Cat, Squirrel Monkey 14 15940501
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody J Neuroendocrinol. 2004 Nov;16(11):916-21. Photoperiod affects neuronal nitric oxide synthase and aggressive behaviour in male Siberian hamsters (Phodopus sungorus). Wen JC1, Hotchkiss AK, Demas GE, Nelson RJ. Hamster IHC 15584932
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Workman, Joanna L., et al. "Post-weaning environmental enrichment alters affective responses and interacts with behavioral testing to alter nNOS immunoreactivity." Pharmacology Biochemistry and Behavior 100.1 (2011): 25-32. 8 21777607
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Miller, Stephen D., et al. "Prenatal Stress?induced Modifications of Neuronal Nitric Oxide Synthase in Amygdala and Medial Preoptic Area." Annals of the New York Academy of Sciences 877.1 (1999): 760-763. Rat ICC 5 10415700
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Gotti, Stefano, et al. "Rapid changes on nitrinergic system in female mouse hippocampus during the ovarian cycle." Journal of chemical neuroanatomy 38.2 (2009): 117-123. Mouse WB 6 19559786
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Rijkers, K., et al. "Rat vagus nerve stimulation model of seizure suppression: nNOS and ?Fos B changes in the brainstem." Journal of chemical neuroanatomy 46.1 (2012): 1-9. Rat IHC 1 23022956
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Misra, Mala, et al. "Restricted patterns of Hoxd10 and Hoxd11 set segmental differences in motoneuron subtype complement in the lumbosacral spinal cord." Developmental biology 330.1 (2009): 54-72. Mouse, Chick IHC 6 19306865
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody J Comp Neurol. 2010 Jul 15;518(14):2710-28. doi: 10.1002/cne.22360. Roles for gamma-aminobutyric acid in the development of the paraventricular nucleus of the hypothalamus. McClellan KM1, Stratton MS, Tobet SA. Mouse IHC 20506472
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Scordalakes, Elka M., Savera J. Shetty, and Emilie F. Rissman. "Roles of estrogen receptor ? and androgen receptor in the regulation of neuronal nitric oxide synthase." Journal of Comparative Neurology 453.4 (2002): 336-344. Mouse ICC 69 12389206
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Dev Neurobiol. 2008 Jun;68(7):981-95. doi: 10.1002/dneu.20638.Sex differences in brain developing in the presence or absence of gonads. Büdefeld T1, Grgurevic N, Tobet SA, Majdic G. Mouse IHC 18418875
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Dominguez, Juan M., et al. "Sexual experience increases nitric oxide synthase in the medial preoptic area of male rats." Behavioral neuroscience 120.6 (2006): 1389. 20 not found
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Blackshaw, S., et al. "Species, strain and developmental variations in hippocampal neuronal and endothelial nitric oxide synthase clarify discrepancies in nitric oxide-dependent synaptic plasticity." Neuroscience 119.4 (2003): 979-990. 83 12831857
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Clancy B1, Silva-Filho M, Friedlander MJ, J Comp Neurol. 2001 May 28;434(2):233-52."Structure and projections of white matter neurons in the postnatal rat visual cortex" Rat IHC 52 11331526
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Song, Chang-Hyun, et al. "Subtle microstructural changes of the striatum in a DYT1 knock-in mouse model of dystonia." Neurobiology of disease 54 (2013): 362-371. Mouse IHC 10 23336980
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody CARDEN, Wm BRECKINRIDGE, and MARTHA E. BICKFORD. "Synaptic inputs of class III and class V interneurons in the cat pulvinar nucleus: differential integration of RS and RL inputs." Visual neuroscience 19.01 (2002): 51-59. Cat 15 12180859
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Martini, Mariangela, Monica Pradotto, and GianCarlo Panzica. "Synergic effects of estradiol and progesterone on regulation of the hypothalamic neuronal nitric oxide synthase expression in ovariectomized mice." Brain research 1404 (2011): 1-9. Mouse 4 21733493
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Travers, Susan P., and Joseph B. Travers. "Taste?evoked Fos expression in nitrergic neurons in the nucleus of the solitary tract and reticular formation of the rat." Journal of Comparative Neurology 500.4 (2007): 746-760. Rat IHC 10 17154256
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Gelman, Diego M., et al. "The embryonic preoptic area is a novel source of cortical GABAergic interneurons." The Journal of Neuroscience 29.29 (2009): 9380-9389. Mouse IF 100 19625528
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Lelos, M. J., et al. "The lateral neostriatum is necessary for compensatory ingestive behaviour after intravascular dehydration in female rats." Appetite 71 (2013): 287-294. Rat 0 24045209
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody de Jongh, R., et al. "The localisation of cyclo-oxygenase immuno-reactivity (COX I-IR) to the urothelium and to interstitial cells in." The interstitial cells of the urinary bladder. 0 18752640
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Mezei, G, The mechanism of estrogen's effect in the hypothalamic regulation of energy homeostasis and circadian rhythm Homeostasis 0 not found
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody J Neurosci. 2011 Jan 5;31(1):359-70. doi: 10.1523/JNEUROSCI.2225-10.2011. The mitochondrial permeability transition pore regulates nitric oxide-mediated apoptosis of neurons induced by target deprivation. Martin LJ1, Adams NA, Pan Y, Price A, Wong M. Mouse WB Apoptosis 21209222
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Wei, B., et al. "The onion skin-like organization of the septum arises from multiple embryonic origins to form multiple adult neuronal fates." Neuroscience 222 (2012): 110-123. 0 not found
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody J Comp Neurol. 2009 Jun 10;514(5):492-506. doi: 10.1002/cne.22015. Variability in the occurrence of nitric oxide synthase immunoreactivity in different populations of rat sympathetic preganglionic neurons. Hinrichs JM1, Llewellyn-Smith IJ. Rat IF 19350665
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Coulombe, Josée, et al. "Loss of UCHL1 promotes age-related degenerative changes in the enteric nervous system." Frontiers in aging neuroscience 6 (2014). Mouse 7 24994982
24287 nNOS:C-Terminal (neuronal Nitric Oxide Synthase) Antibody Llewellyn-Smith, I. J., et al. "Spinally projecting preproglucagon axons preferentially innervate sympathetic preganglionic neurons." Neuroscience 284 (2015): 872-887. Mouse IF 1 not defined

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MSDS

This product contains the preservative sodium azide. The concentration percent of the sodium azide is ≤ .09%. Although this hazardous substance is a concentration below that required for the preparation of a Material Safety Data Sheet, we created a standard MSDS for your records.

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