Alpha-MSH (Melanocyte Stimulating Hormone) Antibody

Alpha-MSH (Melanocyte Stimulating Hormone) Antibody
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Price: $250.00
Product ID : 20074

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Description

The ImmunoStar alpha melanocyte stimulating hormone antiserum was quality control tested using standard immunohistochemical methods. The antiserum demonstrates strongly positive labeling of rat pituitary using biotin/avidin-HRP techniques.

Recommended primary dilution is 1/4000-1/6000 in PBS/0.3% Triton X-100 - Bn/Av-HRP Technique. Staining is completely eliminated by pretreatment of the diluted antibody with 100 ug/mL of alpha-MSH.

Photo Description: IHC image of neurons staining for MSH in the rat hypothalamus (above) and rat pituitary with nickel preparation (below). The tissue was fixed with 4% formaldehyde in phosphate buffer, before being removed and prepared for sectioning. Sections were incubated at RT in 10% goat serum in PBS, before standard IHC procedure. Primary antibody was incubated at 1:5000 for 48 hours, goat anti-rabbit secondary was subsequently added for 1 hour after washing with PBS. Light microscopy staining was achieved with standard biotin-streptavidin/HRP procedure and DAB chromogen. 

MSH pituitary #20074

Host: Rabbit

Quantity / Volume: 100 µL

State: Lyophilized Whole Serum

Reacts With: Pig, Hamster, Human, Monkey, Mouse, Rabbit, Rat, Trout

Availability: In Stock

Alternate Names:  POMC; proopiomelanocortin, anti-Alpha-MSH

RRID:  AB_572218

Immunogen: alpha-MSH

Gene Symbol / ID, Accession #:  POMC,5443

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Publications

PROD # ANTIBODY CITATION SPECIES REACTIVITY APPL METHOD RESEARCH AREA # CITED BY PUBMED ID
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Iwasa, Masamitsu, Kazumi Kawabe, and Hreday N. Sapru. "Activation of melanocortin receptors in the intermediolateral cell column of the upper thoracic cord elicits tachycardia in the rat." American Journal of Physiology-Heart and Circulatory Physiology 305.6 (2013): H885-H893. Rat 0 23832700
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Leitner C1, Bartness TJ, Brain Res. 2009 Oct 6;1292:38-51. doi: 10.1016/j.brainres.2009.07.062. Epub 2009 Jul 28. "Acute brown adipose tissue temperature response to cold in monosodium glutamate-treated Siberian hamsters. Leitner C1, Bartness TJ" Hamster IHC 19643091
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Pigment Cell Res. 1998 Oct;11(5):310-3.Agouti-related maturation and tissue distribution of alpha-Melanocyte Stimulating Hormone in wild-type (AwJ/AwJ) and mutant (Ay/a,a/a) mice.Monroe DG1, Wipf LP, Diggins MR, Matthees DP, Granholm NH. Mouse 2 9877102
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Evans, VINCENT R., et al. "Alpha-melanocyte-stimulating hormone and N-acetyl-beta-endorphin immunoreactivities are localized in the human pituitary but are not restricted to the zona intermedia." Endocrinology 134.1 (1994): 97-106. Human 18 8275975
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Dailey MJ1, Bartness TJ, Brain Res. 2010 Apr 6;1323:94-108. doi:10.1016/j.brainres. 2010.01.078. Epub 2010 Feb 4. "Arcuate nucleus destruction does not block food deprivation-induced increases in food foraging and hoarding" Hamster IHC aging 20138163
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Zheng H1, Patterson LM, Phifer CB, Berthoud HR., Am J Physiol Regul Integr Comp Physiol 2005, Jul; 289(1): R247-58. Epub 2005 Mar 3. "Brain stem melanocortinergic modulation of meal size and identification of hypothalamic POMC projections" Rat IF 15746303
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Physiol Behav. 2007 Oct 22;92(3):507-19. Epub 2007 Apr 29.Cannabinoid-induced hyperphagia: correlation with inhibition of proopiomelanocortin neurons? Ho J1, Cox JM, Wagner EJ. Guinea Pig IF 17532014
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Bäck N, Soinila S, Joh TH, Rechardt L., Histochemistry. 1987;86(5):459-64. "Catecholamine-synthesizing enzymes in the rat pituitary. An immunohistochemical study" Rat 28 2884200
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Levine, Joel M., and Patricia Flynn. "Cell surface changes accompanying the neural differentiation of an embryonal carcinoma cell line." The Journal of neuroscience 6.11 (1986): 3374-3384. 53 3021929
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Koban, Michael, Wei Wei Le, and Gloria E. Hoffman. "Changes in hypothalamic corticotropin-releasing hormone, neuropeptide Y, and proopiomelanocortin gene expression during chronic rapid eye movement sleep deprivation of rats." Endocrinology 147.1 (2006): 421-431. Rat IHC 53 16210372
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Lloyd, Ricardo V., et al. "Corticotroph (Basophil) invasion of the pars nervosa in the human pituitary: Localization of proopiomelanocortin peptides, galanin and peptidylglycine ?-amidating monooxygenase-like immunoreactivities." Endocrine Pathology 4.2 (1993): 86-94. 4 not found
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Clifton, V. L., et al. "Corticotropin-releasing hormone and proopiomelanocortin-derived peptides are present in human myometrium." Journal of Clinical Endocrinology & Metabolism 83.10 (1998): 3716-3721. Human IHC 57 9768689
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Kawabe, Tetsuya, Kazumi Kawabe, and Hreday N. Sapru. "Effect of barodenervation on cardiovascular responses elicited from the hypothalamic arcuate nucleus of the rat." PloS one 7.12 (2012): e53111. Rat 5 23300873
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Bixby, John L., and Louis F. Reichardt. "Effects of antibodies to neural cell adhesion molecule (N-CAM) on the differentiation of neuromuscular contacts between ciliary ganglion neurons and myotubesin vitro." Developmental biology 119.2 (1987): 363-372. IHC 57 3803709
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Ryder, Elizabeth F., Evan Y. Snyder, and Constance L. Cepko. "Establishment and characterization of multipotent neural cell lines using retrovirus vector?mediated oncogene transfer." Journal of neurobiology 21.2 (1990): 356-375. 344 2307979
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Borgquist, Amanda, et al. "Estradiol Negatively Modulates the Pleiotropic Actions of Orphanin FQ/Nociceptin at Proopiomelanocortin Synapses." Neuroendocrinology 98.1 (2013): 60-72. IHC 2 not found
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Nguyen, Que Huong, and Edward J. Wagner. "Estrogen differentially modulates the cannabinoid-induced presynaptic inhibition of amino acid neurotransmission in proopiomelanocortin neurons of the arcuate nucleus." Neuroendocrinology 84.2 (2006): 123-137. Guinea Pig 27 17106183
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Borgquist, Amanda, et al. "Gonadal Steroids Differentially Modulate the Actions of Orphanin FQ/Nociceptin at A Physiologically Relevant Circuit Controlling Female Sexual Receptivity." Journal of neuroendocrinology 26.5 (2014): 329-340. Mouse IHC 0 24617903
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Kloukina, Vaia, et al. "G-protein-gated inwardly rectifying K< sup<+ 3 22465809
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):4016-21. doi: 10.1073/pnas.0800096105. Epub 2008 Feb 25.Hypothalamic neurodegeneration and adult-onset obesity in mice lacking the Ubb polyubiquitin gene.Ryu KY1, Garza JC, Lu XY, Barsh GS, Kopito RR. Mouse IF obesity 18299572
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Eur J Neurosci. 2006 Nov;24(10):2731-40. Hypothalamic proopiomelanocortin (POMC) neurons have a cholinergic phenotype. Meister B1, Gömüç B, Suarez E, Ishii Y, Dürr K, Gillberg L. Rat IF 17156199
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Physiol Behav. 2007 Sep 10;92(1-2):263-71. Epub 2007 May 21.Neurotransmitters in key neurons of the hypothalamus that regulate feeding behavior and body weight. Meister B1. Mouse, Rat IF 34 17586536
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Ogawa, Kazushige, Eiko Suziku, and Kazuyuki Taniguchi. "Immunohistochemical studies on the development of the hypothalamo-hyophysial system in Xenopus laevis." The Anatomical Record 241.2 (1995): 244-254. Frog (Xenopus Laevis) 21 7710140
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Ismailov, Rashad, and George Galdava. "Interrelation of Immune, Antioxidant and Hormonal System Indices and their Influence on Melanogenesis in Patients with Skin Hyper Pigmentation." ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 4.4 (2004). 0 not found
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Reyes, Teresa M., and Paul E. Sawchenko. "Involvement of the arcuate nucleus of the hypothalamus in interleukin-1-induced anorexia." The Journal of neuroscience 22.12 (2002): 5091-5099. Rat IHC 58 12077204
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Madden, John, et al. "Isolation and characterization of opioid peptides from rabbit cerebellum." Journal of neurochemistry 56.6 (1991): 1914-1920. Rabbit 1 2027006
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Ryu, K?Y., et al. "Loss of polyubiquitin gene Ubb leads to metabolic and sleep abnormalities in mice." Neuropathology and applied neurobiology 36.4 (2010): 285-299. Mouse IHC metabolic 6 20002312
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Frost?Mason, Sally, Deepika Walpita, and Linda Mckay. "Melanotropin as a potential regulator of pigment pattern formation in embryonic skin." Pigment Cell Research 3.S2 (1990): 262-265. 4 1329074
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Weihe, E., et al. "Multiplicity of opioidergic pathways related to cardiovascular innervation: differential contribution of all three opioid precursors." Opioid Peptides and Blood Pressure Control. Springer Berlin Heidelberg, 1988. 27-49. 13 not found
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Sheng, Hui Z., et al. "Multistep control of pituitary organogenesis." Science 278.5344 (1997): 1809-1812. 291 9388186
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Soinila, S., J. Lakshmanan, and T. Lahtinen. "Nerve growth factor-like activity in the rat pituitary intermediate lobe." Neuroscience research 6.2 (1988): 123-130. Rat IHC 18 3217050
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Eaker, Ervin Y. "Neurofilament and intermediate filament immunoreactivity in human intestinal myenteric neurons." Digestive diseases and sciences 42.9 (1997): 1926-1932. Human 14 9331157
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Front Neuroanat. 2011 Mar 2;5:11. doi: 10.3389/fnana.2011.00011. eCollection 2011. Ontogenetic distribution of the transcription factor nkx2.2 in the developing forebrain of Xenopus laevis. Domínguez L1, González A, Moreno N. Mouse IHC 82 6194532
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Micevych, Paul E., and Robert P. Elde. "Neurons containing ?-melanocyte stimulating hormone and ?-endorphin immunoreactivity in the cat hypothalamus." Peptides 3.4 (1982): 655-662. Cat IHC 24 6291010
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Sithigorngul, Paisarn, Antony OW Stretton, and Cynthia Cowden. "Neuropeptide diversity in Ascaris: an immunocytochemical study." Journal of Comparative Neurology 294.3 (1990): 362-376. 68 2341616
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Quinn, J., F. P. Eckenstein, and R. W. Baughman. "Novel antigenic determinant expressed in neurons of the dorsolateral hypothalamus in rat and human." Journal of neuroscience research 31.4 (1992): 715-723. Rat, Human 1 1374480
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Przewlocki, Rysard, et al. "Opioid enhancement of calcium oscillations and burst events involving NMDA receptors and L-type calcium channels in cultured hippocampal neurons." The Journal of neuroscience 19.22 (1999): 9705-9715. Rat IHC 64 10559380
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody J Clin Invest. 2005 Apr;115(4):951-8. Epub 2005 Mar 10.PI3K integrates the action of insulin and leptin on hypothalamic neurons. Xu AW1, Kaelin CB, Takeda K, Akira S, Schwartz MW, Barsh GS. Mouse IF 15761497
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Gabrilove, J. L., P. J. Anderson, and N. S. Halmi. "PITUITARY PRO?OPIOMELANOCORTIN?CELL CARCINOMA OCCURRING IN CONJUNCTION WITH A GLIOBLASTOMA IN A PATIENT WITH CUSHING'S DISEASE AND SUBSEQUENT NELSON'S SYNDROME." Clinical endocrinology 25.2 (1986): 117-126. 38 3024876
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Huettner, James E., and Robert W. Baughman. "Primary culture of identified neurons from the visual cortex of postnatal rats." The Journal of neuroscience 6.10 (1986): 3044-3060. Rat IHC 376 3760948
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Berrettini, Wade H., et al. "Pro-opiomelanocortin-related peptides in cerebrospinal fluid: a study of manic-depressive disorder." Psychiatry research 16.4 (1985): 287-302. 17 3003774
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Vinnitsky, V. B., and G. V. Glinsky. "Role of the Binding of Neuropeptides to Blood Plasma Proteins in the Control of Their Blood-Brain Barrier Passage." Annals of the New York Academy of Sciences 496.1 (1987): 278-291. 5 3474972
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Diaz, Shanna, et al. "Sex differences in the cannabinoid modulation of appetite, body temperature and neurotransmission at POMC synapses." Neuroendocrinology 89.4 (2009): 424-440. Guinea Pig, Mouse 22 19136814
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Ramaswamy, S., R. B. Gibbs, and T. M. Plant. "Studies of the Localisation of Kisspeptin Within the Pituitary of the Rhesus Monkey (Macaca mulatta) and the Effect of Kisspeptin on the Release of Non?Gonadotropic Pituitary Hormones." Journal of neuroendocrinology 21.10 (2009): 795-804. Monkey IHC 15 19686451
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Cell Tissue Res. 1985;241(1):1-8. The effect of reserpine on the pars intermedia of the rat pituitary. An electron-microscopic, fluorescence-histochemical and immunohistochemical study.Bäck N, Rechardt L. Rat IHC 10 3161619
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Carnahan, J. F., and P. H. Patterson. "The generation of monoclonal antibodies that bind preferentially to adrenal chromaffin cells and the cells of embryonic sympathetic ganglia." The Journal of neuroscience 11.11 (1991): 3493-3506. 40 1719162
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Cell Tissue Res. 1997 Jun;288(3):497-507. The neuronal system of the saccus vasculosus of trout (Salmo trutta fario and Oncorhynchus mykiss): an immunocytochemical and nerve tracing study.Yáñez J1, Rodríguez M, Pérez S, Adrio F, Rodríguez-Moldes I, Manso MJ, Anadón R. Trout ICC 28 9134862
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Nahon, J. L., et al. "The Rat Melanin-Concentrating Hormone Messenger Ribonucleic Acid Encodes Multiple Putative Neuropeptides Coexpressed in the Dorsolateral Hypothalamus*." Endocrinology 125.4 (1989): 2056-2065. Rat 235 2477226
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Fernandez Jr, Philip Joseph. "The role of alpha-melanocyte stimulating hormone in environmentally induced color change." (1990). 0 not found
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Farhang, Borzoo, et al. "The role of the NOP receptor in regulating food intake, meal pattern, and the excitability of proopiomelanocortin neurons." Neuropharmacology 59.3 (2010): 190-200. Mouse IHC 12 20510254
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody O'Shea, K. Sue, L-HJ Liu, and V. M. Dixita. "Thrombospondin and a 140 kd fragment promote adhesion and neurite outgrowth from embryonic central and peripheral neurons and from PC12 cells." Neuron 7.2 (1991): 231-237. 92 1873028
20074 Alpha-MSH (Melanocyte Stimulating Hormone) Antibody Wang, Hong, et al. "Tankyrases regulate glucoregulatory mechanisms and somatic growth via the central melanocortin system in zebrafish larvae." The FASEB Journal (2015): fj-15. Fish 0 not defined

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MSDS

This product contains the preservative sodium azide. The concentration percent of the sodium azide is ≤ .09%. Although this hazardous substance is a concentration below that required for the preparation of a Material Safety Data Sheet, we created a standard MSDS for your records.

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