SP-1 Chromogranin A (Porcine) Antibody

SP-1 Chromogranin A (Porcine) Antibody
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Price: $250.00
Product ID : 20086
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The antibody has a proven strong Biotin-Streptavidin/HRP staining at a 1/500-1/1000 dilution, in rat adrenal medulla and rat stomach.

Photo Description: IHC image of the rat adrenal medulla staining for SP-1 chomogranin A (porcine) with FITC-conjugated secondary antibody (above) and with standard biotin-streptavidin/HRP and DAB chromogen (below). The tissue was fixed with 4% formaldehyde/0.05% glutaraldehyde in 0.1 M phosphate buffer, before being removed and prepared for vibratome sectioning. Floating sections were incubated at RT in 10% goat serum in PBS, before standard IHC procedure. Primary antibody was incubated at 1:1000 for 48 hours, goat anti-rabbit secondary was subsequently added for 1 hour after washing with PBS.

SP-1 Chromogranin A (Porcine) #20086

Host: Rabbit

Quantity / Volume:  100 µL

State: Lyophilized Whole Serum

Reacts With: Buffalo, Chicken, Cow, Dolphin, Gerbil, Human, Manis Javanica (Sunda Pangolin), Mouse, Pig, Ram (Sheep), Rat, Sea Lion

Alternate Names:  Pituitary secretory protein I; CgA; chromogranin A (parathyroid secretory protein 1)   

Gene Symbol / ID, Accession #:  CHGA, 397540

Availability: In Stock


Download Product Spec. SheetSP-1 Chromogranin A (Porcine) Antibody


Journal References:

A crucial role of WW45 in developing epithelial tissues in the mouse; Joo-Hyeon Lee, Tae-Shin Kim, Tae- Hong Yang, Bon-Kyoung Koo, Sang-Hong Yang, Bon-Kyoung Koo, Sang-Phil Oh, Kwang-Pyo Lee, Hyun-Jung Oh, Sang-Hee Lee, Young-Yun Kong, Jin-Man Kim and Dae-Sik Lim; The EMBO Journal, 27:1231–1242, 2008, Tested in Mouse, PubMed ID: 18369314

Gonzalez, Liara M., et al. "Cell Lineage Identification and Stem Cell Culture in a Porcine Model for the Study of Intestinal Epithelial Regeneration." PloS one 8.6 (2013): e66465. Tested in Pig, PubMed ID: 23840480

Fossmark, Reidar, et al. "The effects of unilateral truncal vagotomy on gastric carcinogenesis in hypergastrinemic Japanese female cotton rats." Regulatory peptides 184 (2013): 62-67. Tested in Rat, PubMed ID: 23499800

Sørdal, Øystein, et al. "The Gastrin Receptor Antagonist Netazepide (YF476) Prevents Oxyntic Mucosal Inflammation Induced by Helicobacter Pylori Infection in Mongolian Gerbils." Helicobacter 18.6 (2013): 397-405. Tested in Gerbil, PubMed ID: 23865485

Russo, Finizia, et al. "Expression and Immunohistochemical Detection of Leptin‐Like Peptide in the Gastrointestinal Tract of the South American Sea Lion (Otaria flavescens) and the Bottlenose Dolphin (Tursiops truncatus)." The Anatomical Record 295.9 (2012): 1482-1493. Tested in Sea Lion and Dolphin, PubMed ID: 22791650

Fjeldbo, Christina Sæten, et al. "Gastrin upregulates the prosurvival factor secretory clusterin in adenocarcinoma cells and in oxyntic mucosa of hypergastrinemic rats." American Journal of Physiology-Gastrointestinal and Liver Physiology 302.1 (2012): G21-G33. Tested in Rat, PubMed ID: 21995960

Ramalingam, Sendhilnathan, et al. "Intestinal Stem Cells in GI Physiology and Disease: Distinct levels of Sox9 expression mark colon epithelial stem cells that form colonoids in culture." American Journal of Physiology-Gastrointestinal and Liver Physiology 302.1 (2012): G10. Tested in Mouse, PubMed ID: 21995959

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Silvia Fre, Edouard Hannezo, Sanja Sale, Mathilde Huyghe, Daniel Lafkas, Holger Kissel, Angeliki Louvi, Jeffrey Greve, Daniel Louvard, Spyros Artavanis-Tsakonas, Notch Lineages and Activity in Intestinal Stem Cells Determined by a New Set of Knock-In Mice, PLoS ONE,6(10):e25785 (2011), Tested in Mouse, PubMed ID: 21991352

Russo, F., et al. "Neuroendocrine cells in the urogenital tract of the buffalo." Italian Journal of Animal Science 6.2s (2010): 792-793. Tested in Buffalo

Formeister, Eric J., et al. "Distinct SOX9 levels differentially mark stem/progenitor populations and enteroendocrine cells of the small intestine epithelium." American Journal of Physiology-Gastrointestinal and Liver Physiology 296.5 (2009): G1108. Tested in Mouse, PubMed ID: 19228882

Zaza Kokrashvili, Deniliz Rodriguez, Valeriya Yevshayeva, Hang Zhou, Robert F. Margolskee, And Bedrich Mosinger, "Release of Endogenous Opioids From Duodenal Enteroendocrine Cells Requires Trpm5", GASTROENTEROLOGY,137:598-606 (2009), Tested in Mouse, PubMed ID: 19272386

Russo, Finizia, et al. "Expression of orexin A and its receptor 1 in the bovine urethroprostatic complex." The anatomical record 291.2 (2008): 169-174. Tested in Cow, PubMed ID: 18213704

Mary Ann S. Crissey, Rong-Jun Guo, Franz Fogt, Hong Li, Jonathan P. Katz, Debra G. Silberg, Eun Ran Suh and John P. Lynch, The Homeodomain Transcription Factor Cdx1 Does Not Behave as an Oncogene in Normal Mouse Intestine, Neoplasia,10:8–19 (2008), Tested in Mouse, PubMed ID: 18231635

Mahoney, Zhen X., Thaddeus S. Stappenbeck, and Jeffrey H. Miner. "Laminin α5 influences the architecture of the mouse small intestine mucosa." Journal of cell science 121.15 (2008): 2493-2502. Tested in Mouse, PubMed ID: 18628307

Lee, Joo‐Hyeon, et al. "A crucial role of WW45 in developing epithelial tissues in the mouse." The EMBO journal 27.8 (2008): 1231-1242. Tested in Mouse, PubMed ID: 18369314

Yuan, Aping, et al. "Chromogranin A-positive tumor cells in human esophageal squamous cell carcinomas." Pathology & Oncology Research 13.4 (2007): 321-325. Tested in Human, PubMed ID: 18158567

Mohamed A. Hamza, Dennis M. Higgins, and William T. Ruyechan; Herpes Simplex Virus Type-1 Latency-Associated Transcript-induced Immunoreactivity of Substance P in Trigeminal Neurons is Reversed by Bone Morphogenetic Protein-7; Neurosci Lett.,413(1):31–35 (2007), Tested in Rat, PubMed ID: 17239535

Pauline Bastide, Charbel Darido, Julie Pannequin, Ralf Kist, Sylvie Robine, Christiane Marty-Double, Frédéric Bibeau, Gerd Scherer, Dominique Joubert, Frédéric Hollande, Philippe Blache, and Philippe Jay; Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium; Journal of Cell Biology,178:635–648 (2007), Tested in Mouse, PubMed ID: 17698607

Yang Wanga, Subir K. Raya, Philip W. Hinds, and Andrew B. Leiter; The retinoblastoma protein, RB, is required for gastrointestinal endocrine cells to exit the cell cycle, but not for hormone expression; Dev Biol.,311(2):478–486 (2007), Tested in Mouse, PubMed ID: 17936268

Bosse, Tjalling, et al. "Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine." Molecular and cellular biology 26.23 (2006): 9060-9070. Tested in Mouse, PubMed ID: 16940177

Nisa, C., et al. "Immunohistochemical study on the distribution and relative frequency of endocrine cells in the stomach of the Malayan pangolin, Manis javanica." Anatomia, histologia, embryologia 34.6 (2005): 373-378. Tested in Manis Javanica (Sunda Pangolin), PubMed ID: 16288608

Takaishi, Shigeo, et al. "Synergistic Inhibitory Effects of Gastrin and Histamine Receptor Antagonists on  Helicobacter  -Induced Gastric Cancer." Gastroenterology 128.7 (2005): 1965-1983. Tested in Mouse, PubMed ID: 15940630

Blair B. Madison, Katherine Braunstein, Erlene Kuizon, Kathleen Portman, Xiaotan T. Qiao, Deborah L. Gumucio; Epithelial hedgehog signals pattern the intestinal crypt-villus axis; Development,132:279-289 (2004), Tested in Mouse, PubMed ID: 15590741

Guanglin Cui, Theodore J. Koh, Duan Chen, Chun-Mei Zhao, Shigeo Takaishi, Graham J. Dockray, Andrea Varro, Arlin B. Rogers, James G. Fox, and Timothy C. Wang; Overexpression of Glycine-Extended Gastrin Inhibits Parietal Cell Loss and Atrophy in the Mouse Stomach; CANCER RESEARCH,64:8160-8166 (2004), Tested in Mouse, PubMed ID: 15548680

Bakke, I., A. K. Sandvik, and H. L. Waldum.; "Octreotide inhibits the enterochromaffin-like cell but not peroxisome proliferator-induced hypergastrinemia." Journal of molecular endocrinology 25.1 (2000): 109-119. Tested in Rat, PubMed ID:     10915223

Kameda, Yoko, Masaaki Miura, and Yoshiaki Hayashida. "Different effects of prolonged isocapnic hypoxia on the carotid body and the glomus cells in the wall of the common carotid artery of the chicken." Brain research 805.1 (1998): 191-206.    Tested in Chicken, PubMed ID: 9733964

Friis-Hansen, Lennart, et al. "Impaired gastric acid secretion in gastrin-deficient mice." American Journal of Physiology-Gastrointestinal and Liver Physiology 274.3 (1998): G561-G568. Tested in Mouse, PubMed ID: 9530158    

Fukunaga, Masaharu. "Neuroendocrine carcinoma of the breast with Merkel cell carcinoma‐like features." Pathology international 48.7 (1998): 557-561., PubMed ID: 9701020

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Fukunaga, Masaharu, et al. "Small cell neuroendocrine carcinoma of the ovary." Virchows Archiv 430.4 (1997): 343-348. PubMed ID: 9134047

Czaja, K., et al. "Neuroendocrine cells in the female urogenital tract of the pig, and their immunohistochemical characterization." Cells Tissues Organs 157.1 (1996): 11-19. Tested in Pig, PubMed ID: 9096738

Yamatsu, Yoshiyasu, and Yoko Kameda. "Accessory carotid body within the parathyroid gland III of the chicken." Histochemistry and cell biology 103.3 (1995): 197-204., Tested in Chicken, PubMed ID: 7553133

Beham, A., et al. "Malignant paraganglioma of the uterus." Virchows Archiv A 420.5 (1992): 453-457. PubMed ID: 1595196

Vittoria, A., et al. "Serotonin-, somatostatin-and chromogranin A-containing cells of the urethro-prostatic complex in the sheep. An immunocytochemical and immunofluorescent study." Journal of anatomy 171 (1990): 169. Tested in Ram and Sheep, PubMed ID: 1981998

Barbareschi, M., et al. "Bronchial carcinoid with paranuclear fibrillary inclusions related to cytokeratins and vimentin." Virchows Archiv A 415.1 (1989): 31-37. PubMed ID: 2472031

Hartschuh, W., E. Weihe, and N. Yanaihara. "Immunohistochemical analysis of chromogranin A and multiple peptides in the mammalian Merkel cell: further evidence for its paraneuronal function." Arch Histol Cytol 52.Suppl (1989): 423-431. PubMed ID: 2510797

Fujita, Tsuneo. "Present status of paraneuron concept." Arch. Histol. Cytol 52 (1989): 1-8., PubMed ID: 2510774

Bretherton-Watt, D., et al. "Pancreastatin distribution and plasma levels in the pig." Peptides 9.5 (1988): 1005-1014. Tested in Pig, PubMed ID: 3244555

Zabel, M., J. Surdyk, and I. Biela-Jacek. "Immunocytochemical studies on thyroid parafollicular cells in postnatal development of the rat." Cells Tissues Organs 130.3 (1987): 251-256. Tested in Rat, PubMed ID: 2893508

Barbareschi, M., et al. "S-100 protein in human lung neuroendocrine neoplasms. Immunohistochemical study of 14 cases and review of the literature." (1987). Tested in Human, PubMed ID: 2856552    

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