SP-1 Chromogranin A (Bovine) Antibody

The antibody has a proven strong staining at a 1/1000 - 1/2000 dilution in rat adrenal medulla using Biotin-Streptavidin/HRP detection method.

Host: Rabbit

Quantity / Volume:  100 µL

State: Lyophilized Whole Serum

Reacts With: Human, Mouse, Rat

Availability: In Stock

Alternate Names:  Pituitary secretory protein I; CgA; chromogranin A (parathyroid secretory protein 1)  

Gene Symbol / ID, Accession #:   CHGA,281070

Download Product Spec. Sheet:  SP-1 Chromogranin A (Bovine) Antibody

Journal References:

Expression analysis of the Islet-1 gene in the developing and adult gastrointestinal tract; Pragnya Das, Catherine Lee May; Gene Expr Patterns, 11(3-4):244-54, 2011, Tested in Mouse, IFC, Cites Diasorin AKA ImmunoStar, PubMed ID: 21220053

Trefoil Peptide Gene Expression in Small Intestinal Crohn's Disease and Dietary Adaptation; Poulsom R, Chinery R, Sarraf C, Van Noorden S, Stamp GW, Lalani EN, Elia G, Wright NA.; Journal of Clinical Gastroenterology, 17(S1):S78-S91, 1993, Tested in Human and Rat, Cites Incstar AKA ImmunoStar, PubMed ID: 8283019

Examining the Role of Paneth Cells in the Small Intestine by Lineage Ablation in Transgenic Mice; Garabedian EM , Robberts  LJJ , McNevin MS; The Journal of Biological Chemistry, 272(38):23729-23740, 1997, Tested in Mouse, IFC, Cites Incstar AKA ImmunoStar, PubMed ID: 9295317

Ablation of a Critical Surfactant Protein B Intramolecular Disulfide Bond in Transgenic Mice, Beck DC, Na CL , Whitsett  JA ; The Journal of Biological Chemistry, 275(5):3371-3376, 2000, Tested in Mouse, IFC, Cites Incstar AKA ImmunoStar, PubMed ID: 10652328

Energy Homeostasis and Gastrointestinal Endocrine Differentiation Do Not Require the Anorectic Hormone Peptide YY; Schonhoff S, Baggio L, Ratineau  C, Ray SK, Lindner J , Magnuson MA, Drucker DJ , and Leiter AB; American Society for Microbiology, 25.1:4189-4199, 2005, Tested in Mouse, PubMed ID: 15870288

Evidence for a p27 tumor suppressive function independent of its role regulating cell proliferation in the prostate ; Shaffer DR, Ryota Ishiwata AV, Leversha M, Olgac  S , Manova K, Satagopan, J, Scher H  and Koff A, ; PNAS, 102:210-215 , 2004, Tested in Mouse, PubMed ID: 15615849

Epithelial hedgehog signals pattern the intestinal crypt-villus axis; Madison, Braunstein, Kuizon, Portman, Qiao, Gumucio ; Development, 132 (2):279-289, 2005, Tested in Mouse, PubMed ID: 15590741

Mtgr1 Is a Transcriptional Corepressor That is Requried for Maintenance of the Secretory Cell Lineage in the Small Intestine; Amann, Chyla, Ellis, Martinez, Moore, Franklin, McGhee, Meyers,  Ohm, Luce, Ouelette, Washington, Thompson, King,  Gautam, Coffey, Whitehead, Hiebert; Molecular & Cellular Biology, 25(21):9576-9585, 2005, Tested in Mouse, PubMed ID: 16227606

Foxa1 and Foxa2 Control the Differentiation of Goblet and Enteroendocrine L- and D-Cells in Mice; Diana Z. Ye, Klaus H. Kaestner; Gastroenterology, 8:1-43, 2009, Tested in Mouse, PubMed ID: 19737569

Intestinal Subepithelial Myofibroblasts Support in vitro and in vivo Growth of Human Small Intestinal Epithelium; Lahar N, Lei NY, Wang J, Jabaji Z, Tung SC, Joshi V, Lewis M, Stelzner M, Martín MG, Dunn JC.; PLoS ONE, 6(11):e26898, 2011, Tested in Human, PubMed ID: 22125602

Molecular Properties of Adult Mouse Gastric and Intestinal Epithelial Progenitors in Their Niches; Giannakis, Stappenbeck, Mills, Leip, Lovett, Clifton,  Ippolito, Glasscock, Arumugam, Brent, and Gordon; J. Biol. Chem., 281(16):11292-11300, 2006, Tested in Mouse, PubMed ID: 16464855

The Zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic   cells and intestinal endocrine cells; Mathias S. Gierl, Nikolaos Karoulias, Hagen Wende, Michael Strehle, and Carmen Birchmeier; Max-Delbrück-Center for Molecular Medicine,:, 2006, Tested in Mouse, PubMed ID: 16951258

Enteroendocrine precursors differentiate independently of Wnt and form serotonin expressing adenomas in response to active b-catenin; Yang Wang, Maryann Giel-Moloney, Guido Rind, and Andrew B. Leiter; PNAS, 104:1328–11333, 2007, Tested in Mouse, PubMed ID: 17592150

Homeodomain transcription factor NKX2.2 functions in immature cells to control enteroendocrine differentiation and is expressed in gastrointestinal tumors; Yu-Cheng Wang, Emerick Gallego-Arteche, Gioia Iezza, Xiaochen Yuan, Mary R Matli, Su-PinChoo, Marlene B Zuraek, Ravi Gogia, Francis C Lynn, Michael S German, Emily K Bergsland, David B Donner, Robert S Warren, and Eric Kakakura; Endocrine-Related Cancer, 16:267–27, 2009, Tested in Mouse, PubMed ID: 18987169

Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2; Verzi MP, Shin H, He HH, Sulahian R, Meyer CA, Montgomery RK, Fleet JC, Brown M, Liu XS, Shivdasani RA.; Dev Cell., 19(5):713-26, 2010, Tested in Mouse, PubMed ID: 21074721

Essential and Redundant Functions of Caudal Family Proteins in Activating Adult Intestinal Genes; Michael P. Verzi, Hyunjin Shin, Li-Lun Ho, X. Shirley Liu, Ramesh A. Shivdasani; Mol Cell Biol, 31(10):2026–2039, 2011, Tested in Mouse, PubMed ID: 21402776

Delta1 Expression, Cell Cycle Exit, and Commitment to a Specific Secretory Fate Coincide within a Few Hours in the Mouse Intestinal Stem Cell System; Despina Stamataki, Maxine Holder, Christine Hodgetts1, Rosemary Jeffery, Emma Nye, Bradley Spencer-Dene, Douglas J. Winton, Julian Lewis; PLoS ONE, 6(9):e24484, 2011, Tested in Mouse, PubMed ID: 21915337

Epithelial BMP signaling is required for proper specification of epithelial cell lineages and gastric endocrine cells; Faïza Maloum, Joannie M. Allaire, Jessica Gagné-Sansfaçon, Evelyne Roy, Karine Belleville, Philippe Sarret, Jean Morisset, Julie C. Carrier, Yuji Mishina, Klaus H. Kaestner, Nathalie Perreault; Am J Physiol Gastrointest Liver Physio, 300(6):G1065–G1079, 2011, Tested in Mouse, PubMed ID: 21415412

Dual regulatory role for phosphatase and tensin homolog in specification of intestinal endocrine cell subtypes; Sébastien AB Roy, Marie-Josée Langlois, Julie C Carrier, François Boudreau, Nathalie Rivard, Nathalie Perreault; World J Gastroenterol, 18(14):1579-1589, 2012, Tested in Mouse, PubMed ID: 22529686