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nNOS:C-Terminal (Neuronal Nitric Oxide Synthase)

nNOS:C-Terminal (Neuronal Nitric Oxide Synthase)
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Price: $310.00
Product ID : 24287
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Description

The ImmunoStar neuronal nitric oxide synthase C-terminal antiserum was quality control tested using standard immunohistochemical methods. The antiserum demonstrates strongly positive labeling of rat hypothalamus, striatum, cortex and spinal cord using indirect immunofluorescent and biotin/avidin-HRP techniques. Recommended primary dilutions are 1/1,000 - 1/1,500 in PBS/0.3% Triton X-100 - Cy3 Technique and 1/8,000 - 1/12,000 in PBS/0.3% Triton X-100 - Bn/Av-HRP Technique.

By Western blot analysis of brain homogenates the antibody specifically labels a band of approximately 155 kD. Immuno-labeling is completely abolished by pre-adsorption with synthetic human nNOS (1419-1433) at 5 µg per mL of diluted antibody. No cross reactivity with other forms of NOS were observed. 

 

Host: Rabbit

Quantity / Volume:  100 µL

State: Lyophilized Whole Serum

Reacts With: Hamster, Mouse, Rat

Availability: In Stock

Alternate Names:  Constitutive NOS; NC-NOS; NOS type I; Neuronal NOS; Nitric Oxide Synthase; bNOS; Nitric oxide synthase-brain; N-NOS; Peptidyl-cysteine S-nitrosylase; IHPS1; NC-NOS; nitric oxide synthase 1 (neuronal)

Gene Symbol / ID, Accession #:  NOS1, 4842

 

Download Product Spec. SheetnNOS:C-Terminal Antibody

 

Journal References:


Innervation of the rat uterus at estrus: a study in full-thickness, immunoperoxidase-stained whole-mount preparations; Gnanamanickam GJ, Llewellyn-Smith IJ; J Comp Neurol., 519(4):621-43, 2011, Tested in Rat, Cites Diasorin AKA ImmunoStar, PubMed ID: 21246547

Neuronal Nitric Oxide Synthase Activation and Peroxynitrite Formation in Ischemic Stroke Linked to Neural Damage; Eliasson MJL, Huang Z, Ferrante RJ; The Journal of Neuroscience,19(14):5910-5918, 1999, Tested in Mouse, Cites Incstar AKA ImmunoStar, PubMed ID: 10407030

Rapid changes on nitrinergic system in female mouse hippocampus during the ovarian cycle; Stefano Gotti, Mariangela Martini, Monica Pradotto, Carla Viglietti-Panzica, GianCarlo Panzica; Journal of Chemical Neuroanatomy, 38:117–123, 2009, Tested in Mouse, Cites Incstar AKA ImmunoStar, PubMed ID: 19559786

Neuronal nitric oxide synthase alternatively spliced forms:  Prominent functional localizations in the brain; Mikael J. L. Eliasson, Seth Blackshaw,  Michael J. Schell, And Solomon H. Snyder; Proc. Natl. Acad. Sci. USA, Vol. 94:pp. 3396–3401, 1997, Tested in Mouse, IFC, Cites Incstar AKA ImmunoStar, PubMed ID: 9096405

The Mitochondrial Permeability Transition Pore Regulates Nitric Oxide-Mediated Apoptosis of Neurons Induced by Target Deprivation; Lee J. Martin, Neal A. Adams, Yan Pan, Ann Price, Margaret Wong; J Neurosci,31(1):359 -70, 2011, Tested in Mouse, Western Blot, PubMed ID: 21209222

Photoperiod Affects Neuronal Nitric Oxide synthase and Aggressive Behaviour in Male Siberian Hamsters (Phodopus sungorus); Wen JC, Hotchkiss AK, Demast GE, Nelson RJ; Journal of Neuroendocrinology, 16:916-921, 2004, Tested in Hamster, PubMed ID: 15584932

Distribution of Nitric Oxide Synthase Immunoreactivity in the Mouse Brain; Gotti, Sica, Viglietti-Panzica, Panzica; Microscopy Research and Technique, 68:13-35, 2005, Tested in Mouse, PubMed ID: 16208717

Impaired Nitric Oxide Synthase Signaling Dissociates Social Investigation and Aggression; Brian C. Trainor, Joanna L. Workman, Ruth Jessen, and Randy J. Nelson; Behav Neurosci, 121:362-369, 2007, Tested in Mouse, PubMed ID: 17469926

Sex differences in brain developing in the presence or absence of gonads; Tomaz Büdefeld, Neza Grgurevic, Stuart A. Tobet, and Gregor Majdic; Dev Neurobiol., 68(7):981-995, 2008, Tested in Mouse, PubMed ID: 18418875

Roles for c-Aminobutyric Acid in the Development of
the Paraventricular Nucleus of the Hypothalamus; ; J Comp Neurol, 518(14):2710-28, 2010, Tested in Mouse, PubMed ID: 20506472

Lis1 reduction causes tangential migratory errors in mouse spinal cord; Moore KD, Chen R, Cilluffo M, Golden JA, Phelps PE; J Comp Neurol., 520(6):1198-211, 2012, Tested in Mouse, PubMed ID: 21935943

Tyrosine-phosphorylated and nonphosphorylated isoforms of alpha-dystrobrevin: roles in skeletal muscle and its neuromuscular and myotendinous junctions; R. Mark Grady, Mohammed Akaaboune, Alexander L. Cohen, Margaret M. Maimone, Jeff W. Lichtman, and Joshua R. Sanes; The Journal of Cell Biology, 160:741-752, 2003, Tested in Mouse, PubMed ID: 12604589

Layer Acquisition by Cortical GABAergic Interneurons Is Independent of Reelin Signaling; Ramon Pla, Vıctor Borrell, Nuria Flames, and Oscar Marın; Journal of Neuroscience, 26(26):6924–6934, 2006, Tested in Mouse, PubMed ID: 16807322

Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death; Martin LJ, Liu Z, Chen K, Price AC, Pan Y, Swaby JA, Golden WC.; J Comp Neurol., 500(1):20-46, 2007, Tested in Mouse, PubMed ID: 17099894

Estrogen modulates neuronal movements within the developing preoptic area/anterior hypothalamus; John Gabriel Knoll, Cory A. Wolfe, and Stuart A. Tobet; Eur J Neurosci., 26(5):1091-1100, 2008, Tested in Mouse, PubMed ID: 17767488

A novel O2-sensing mechanism in rat glossopharyngeal neurones mediated by a halothane-inhibitable background K+ conductance; Verónica A. Campanucci, Ian M. Fearon and Colin A. Nurse; J Physiol, 548.3:731-743, 2003, Tested in Rat, PubMed ID: 12640017

Taste-evoked Fos expression in nitrergic neurons in the nucleus of the solitary tract and reticular formation of the rat; Travers SP, Travers JB.; J Comp Neurol., 500(4):746-60, 2007, Tested in Rat, PubMed ID: 17154256

Variability in the occurrence of nitric oxide synthase immunoreactivity in different populations of rat sympathetic preganglionic neurons; Hinrichs JM, Llewellyn-Smith IJ.; J Comp Neurol., 514(5):492-506, 2009, Tested in Rat, PubMed ID: 19350665

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