Gastrin Releasing Peptide (GRP) / Bombesin Antibody

The ImmunoStar Gastrin Releasing Peptide antiserum was quality control tested using standard immunohistochemical methods. The antiserum demonstrates strongly positive labeling of rat dorsal horn of spinal cord using indirect immunofluorescent and biotin/avidin-HRP techniques. Recommended primary dilutions are 1/400-1/600 in PBS/0.3% Triton X-100 - Cy3 Technique and 1/1,000-1/2,000 in PBS/0.3% Triton X-100 - Bn/Av-HRP Technique. Staining is completely eliminated by pretreatment of 1 mL of diluted antibody with 50 µg of bombesin.

Host: Rabbit

Quantity / Volume: 100 µL

State: Lyophilized Whole Serum

Reacts With:  Hamster, Human, Mouse, Rat

Predicted to React With: Bovine, Sheep

Availability: In Stock

Preabsorption Control: Available at irbiologicals, Catalog # IRCP069.  Sequence: Glp-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH

Alternate Names:  BN; GRP-10; proGRP; preproGRP; gastrin-releasing peptide

Gene Symbol / ID, Accession #:  GRP,2922

Download Product Spec Sheet:  Gastrin Releasing Peptide (Bombesin) Antibody

Journal References:

Diffuse Lung Disease in Young Children; Gail H. Deutsch, Lisa R. Young, Robin R. Deterding, Leland L. Fan, Sharon D. Dell, Judy A. Bean; Am J Respir Crit Care Med,176:1120-1128, 2007, Tested in Human , PubMed ID: 17885266

ORL1 receptor-mediated down-regulation of mPER2 in the suprachiasmatic nucleus accelerates re-entrainment of the circadian clock following a shift in the environmental light/dark cycle; Kazuko Miyakawa , Ayumi Uchida, Tomomi Shiraki , Koji Teshima , Hiroshi Takeshima , Shigenobu Shibata; Neuropharmacology,52:52, 2007, Tested in Mouse, PubMed ID: 17196226

Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced Pruritus; Liu Q, Tang Z, Surdenikova L, Kim S, Patel KN, Kim A, Ru F, Guan Y, Weng HJ, Geng Y, Undem BJ, Kollarik M, Chen ZF, Anderson DJ, Dong X.; Cell,139(7):1353-65, 2009, Tested in Mouse, PubMed ID: 20004959

Investigating the role of substance P in photic responses of the circadian system: Individual and combined actions with gastrin-releasing peptide; Roxanne Sterniczuk, Mark A. Colijn, Maria Nunez, Michael C. Antle ; Neuropharmacology,:1–9, 2009, Tested in Hamster, PubMed ID: 19540856

A gastrin-releasing peptide receptor mediates; Yan-Gang Sun & Zhou-Feng Chen; Nature,448:700-703, 2007, Tested in Mouse, PubMed ID: 17653196

Serotonergic potentiation of photic phase shifts: Examination of receptor contributions and early biochemical / molecular events; Victoria M. Smith, Kimberly Hagel, Michael C. Antle; J.Neuroscience,4522(09:1-51, 2009, Tested in Mouse, PubMed ID: 19799970

TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice; Tong Liu,1 Temugin Berta,1 Zhen-Zhong Xu,1 Chul-Kyu Park, Ling Zhang, Ning Lü, Qin Liu,Yang Liu, Yong-Jing Gao, Yen-Chin Liu, Qiufu Ma, Xinzhong Dong, and Ru-Rong Ji; The Journal of Clinical Investigation,122(6):2195-2207, 2012, Tested in Mouse, PubMed ID: 22565312

Bombesin, Serotonergic potentiation of photic phase shifts: Examination of receptor contributions and early biochemical / molecular events, Victoria M. Smith, Kimberly Hagel, Michael C. Antle, J.Neuroscience, 4522(09, 1-51, 2009, mice