CGRP (Calcitonin Gene Related Peptide) Antibody

The antibody has a proven fluorescein staining at a 1/100-1/200 dilution and a strong Biotin-Streptadvidin/HRP staining at a 1/2000-1/4000 dilution in rat amygdala, and spinal cord.

The specificity of the antiserum was evaluated by soluble pre-adsorption with the peptides in question at a final concentration of 10-5M. CGRP immunolabeling was completely abolished by pre-adsorption with rat α -CGRP and partially eliminated by pre-adsorption with rat Ÿ -CGRP. Pre-adsorption with the following peptides resulted in no loss of immunostaining: rat amylin, rat adrenomedulin, calcitonin, neurotensin, somatostatin, substance P, leucine enkephalin, methionine enkephalin, VIP, CCK-8, vasopressin and neuropeptide Y.

Host: Rabbit

Quantity / Volume:  100 µL

State: Lyophilized Whole Serum

Reacts With: Human, Pig, Rat

Availability: In Stock


Download Product Spec. Sheet:  CGRP (Calcitonin Gene Related Peptide) Antibody

Journal References:

1. Expression of Vanilloid Receptor TRRV1 in the Rat Trigeminal Sensory Nuclei, Bae, Oh, Hwang, Shigenaga, Valtschanoff, The Journal of  Comparative Neurology, 478, 62-71, 2004.

2. Immunocytochemical study on the liver innervation in patients with cirrhosis., Stoyanova II, Gulubova MV, acta histochem, 102, 391-402, 2000. 

3. The majority of bladder sensory afferents to the rat lumbosacral spinal cord are both IB4- and CGRP-positive, Hwang, Oh, Valtschanoff, Brain Research, 1062, 86-91, 2005.

4. Anatomical Evidence for Enteric Neuroimmune Interactions in Peyer’s Patches, Lucy Vulchanova, Melissa A. Casey, Gwen W. Crabb, William R. Kennedy, and David R. Brown, J Neuroimmunol., 185, 64-74, 2007, Tested in Pig.