Alpha-MSH (Melanocyte Stimulating Hormone) Antibody

The ImmunoStar alpha melanocyte stimulating hormone antiserum was quality control tested using standard immunohistochemical methods. The antiserum demonstrates strongly positive labeling of rat pituitary using biotin/avidin-HRP techniques.

Recommended primary dilutions are 1/100-1/200 in PBS/0.3% Triton X-100 - FITC Technique and 1/4000-1/6000 in PBS/0.3% Triton X-100 - Bn/Av-HRP Technique. Staining is completely eliminated by pretreatment of the diluted antibody with 100 ug/mL of alpha-MSH.

Host: Rabbit

Quantity / Volume: 100 µL

State: Lyophilized Whole Serum

Reacts With: Guinea Pig, Mouse, Rat

Availability: In Stock

Download Product Spec Sheet: Alpha-MSH (Melanocyte Stimulating Hormone) Antibody

Journal References:

Alpha-MSH, Food deprivation-induced changes in body fat mobilization after neonatal monosodium glutamate treatment, Claudia Leitner and Timothy J. Bartness, American Journal of Physiology, 294, R775-R783, 2008, hamster

Alpha-MSH, Acute brown adipose tissue temperature response to cold in monosodium glutamate-treated Siberian hamsters, Claudia Leitner, Timothy J. Bartness, BRAIN RESEARCH, 1292, 3 8 – 5 1, 2 0 0 9, hamster

Alpha-MSH, Hypothalamic neurodegeneration and adult-onset obesity in mice lacking the Ubb polyubiquitin gene, Kwon-Yul Ryu, Jacob C. Garza, Xin-Yun Lu, Gregory S. Barsh, and Ron R. Kopito, PNAS, 105, 4016–4021, 2008, mice

Brainstem melanocortinergic modulation of meal size and identification of hypothalamic POMC projections, Zheng, Patterson, Phifer, Berthoud, (1-29), 2005.

PI3K integrates the action of insulin and leptin on hypothalamic neurons, Xu AW, Kaeli CB, Takeda K, Akira S, Schwartz AW and Barsh GS, JCI, 115, 951-958 , 2005.

Hypothalamic proopiomelanocortin (POMC) neurons have a cholinergic phenotype., Bjorn Meister, Burc¸ak Gomuc¸, Elisabet Suarez, Yuko Ishii, Katrin Durr and Linda Gillberg, European Journal of Neuroscience, Vol. 24, pp. 273-2740, 2006.

Cannabinoid-Induced Hyperphagia: Correlation With Inhibition Of Proopiomelanocortin Neurons?, Jennie Ho, Jeremy M. Cox, and Edward J. Wagner, Physiol Behav., 92(3), 507-519, 2007, Tested in Guinea pig.

Hypothalamic neurodegeneration and adult-onset obesity in mice lacking the Ubb polyubiquitin gene, Kwon-Yul Ryu, Jacob C. Garza, Xin-Yun Lu, Gregory S. Barsh, and Ron R. Kopito, Pnas, 105, 4016-4021, 2008, Tested in Mice.