ACTH (Adrenocorticotropic Hormone) Antibody

The antibody produces a maximum fluorescein staining at a 1/100 - 1/200 dilution and a biotin-streptavidin/HRP staining at a 1/500 - 1/1000 dilution in rat anterior/intermediate pituitary. Optimal dilution will vary depending upon fixation, labeling technique and/or detection system; therefore, a dilution series is recommended. The recommened dilution series are 1/100-1/200 in PBS/0.3% Triton X-100 - FITC Technique and 1/500-1/1000 in PBS/0.3% Triton X-100 - Bn-SA/HRP Technique. Staining is completely eliminated by pretreatment of the diluted antibody with 100 µg/mL of ACTH.

Host: Rabbit

Quantity / Volume: 100 µL

State: Lyophilized Whole Serum

Availability: In Stock

Reacts With: Rat

Gene Symbol / ID, Accession #:  POMC, 396863

Download Product Spec Sheet: ACTH (Adrenocorticotropic Hormone) Antibody

Journal References:

Selective Localization of the Parathyroid Secretory Protein-I/Adrenal Medulla Chromogranin A Protein Family in a Wide Variety of Endocrine Cells of the Rat; David V. Cohn, James J. Elting, Mary Frick, Robert Elde; Endocrinology,114(6):1963-1974, 1984, Tested in Rat, IFC, Cites Immuno Nuclear AKA ImmunoStar, PubMed ID: 6233131

Estrogen Impairs Glucocorticoid Dependent Negative Feedback On The Hypothalamic–Pituitary–Adrenal Axis Via Estrogen Receptor Alpha Within The Hypothalamus; M. J. Wwiser and R. J. Handa; Neuroscience,159:883-895, 2009, Tested in Rat, PubMed ID: 19166915